PNOĒ Portable Metabolic Analyzer Validation Report

PNOĒ Portable Metabolic Analyzer Validation Report

The PNOĒ portable metabolic analyzer received independent validation by a multicentre committee of experts from Georgetown University in Washington, The Washington DC VA Medical Center, Rutgers University in New Jersey and Harokopio University in Athens, Greece.

The study showed that the PNOĒ metabolic analyzer provides accuracy and reproducibility equivalent to the COSMED Quark CPET, the gold standard clinical standard in the field of cardio-metabolic testing.
PNOĒ provides superior accuracy compared to other portable systems like the COSMED K5 and the Korr CardioCoach.

Validation Report Overview

Assessment of the oxygen and carbon dioxide content of expired air during exercise is critical for determining cardiorespiratory status. The purpose of this study was to compare the new portable metabolic analyzer PNOĒ with COSMED – Quark CPET, a previously validated stationary metabolic cart. Methods: A total of 22 subjects (17 male and 5 female) aged 32.3 ± 11.1 years took part in the study. Breath by breath gas exchange was measured by both devices during a four-stage incremental protocol on a cycle ergometer. On a separate day, 10 participants repeated the trial to assess the reliability of the PNOĒ metabolic cart. Results: Strong correlations were obtained in VO2 (r=0.98, p<0.001), VCO2 (r=0.98, p<0.001), VE (r=0.98, p<0.001) and RQ (r=0.91, p<0.001), between the two devices. Bland-Altman plots revealed a mean difference of 34.0 ± 118 ml/min and 36.4 ± 110 ml/min in VO2 and VCO2 analysis, respectively. There were no significant differences in VO2, VCO2, VE, or RQ between the two devices. Intraclass correlation coefficient was high between the two trials for VO2 (r=0.98, p<0.001), VCO2 (r=0.98, p<0.001), VE (r=0.99, p<0.001) and RQ (r=0.93, p<0.001). Conclusions: Our data indicate that the portable metabolic cart PNOĒ can accurately determine respiratory gases over a wide range of exercise intensities, in healthy individuals, in a controlled laboratory setting.



Benefits of the PNOE Metabolic Analyzer System

You’ve seen the accuracy with the validation reports.

Here are additional benefits with your investment in PNOE: 
– 2x – 5x lower acquisition cost compared to any other metabolic analyzer in the market
– Real time data transmission to the PNOĒ mobile application
– Real time data transmission to the PNOĒ cloud platform which provides all the tools that other medical grade cardio-metabolic analysis software suites provide
– A suite of services that can skyrocket your business revenue from day 1 including assessment reports custom branded with you company, diet creation from our team of nutrition experts and much more!
Get in touch today to learn why more than 30 universities and more than 500 fitness centers in the US now use PNOĒ for research, weight loss, performance optimization, bike fitting, cardiovascular disease prevention and management and many more exciting applications!

Learn About the PNOĒ PrecisionDiet™ Service

It’s a new service for health and fitness professionals based on clinically accurate metabolic testing with the PNOĒ Metabolic Analyzer.  Help your clients succeed in all their health and weight loss goals with revolutionary precision and coaching support for monthly nutrition, diet, workouts and tracking.  Get more details at

Interested in using the PNOE Metabolic Analzyer for your own business or personal use, to measure and analyze metabolism and to help calibrate smartwatches and wearables?  Get in touch with us below.