PNOĒ Portable Metabolic Analyzer Validation Report
The PNOĒ portable metabolic analyzer received independent validation by a multicentre committee of experts from Georgetown University in Washington, The Washington DC VA Medical Center, Rutgers University in New Jersey and Harokopio University in Athens, Greece.
Validation Report Overview
Assessment of the oxygen and carbon dioxide content of expired air during exercise is critical for determining cardiorespiratory status. The purpose of this study was to compare the new portable metabolic analyzer PNOĒ with COSMED – Quark CPET, a previously validated stationary metabolic cart. Methods: A total of 22 subjects (17 male and 5 female) aged 32.3 ± 11.1 years took part in the study. Breath by breath gas exchange was measured by both devices during a four-stage incremental protocol on a cycle ergometer. On a separate day, 10 participants repeated the trial to assess the reliability of the PNOĒ metabolic cart. Results: Strong correlations were obtained in VO2 (r=0.98, p<0.001), VCO2 (r=0.98, p<0.001), VE (r=0.98, p<0.001) and RQ (r=0.91, p<0.001), between the two devices. Bland-Altman plots revealed a mean difference of 34.0 ± 118 ml/min and 36.4 ± 110 ml/min in VO2 and VCO2 analysis, respectively. There were no significant differences in VO2, VCO2, VE, or RQ between the two devices. Intraclass correlation coefficient was high between the two trials for VO2 (r=0.98, p<0.001), VCO2 (r=0.98, p<0.001), VE (r=0.99, p<0.001) and RQ (r=0.93, p<0.001). Conclusions: Our data indicate that the portable metabolic cart PNOĒ can accurately determine respiratory gases over a wide range of exercise intensities, in healthy individuals, in a controlled laboratory setting.
Benefits of the PNOE Metabolic Analyzer System
You’ve seen the accuracy with the validation reports.
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